Last application date May 15, 2024 00:00
Department GE31 - Department of Biomolecular Medicine
Contract Limited duration
Degree Master’s degree in Medicine, Biomedical Sciences, Biotechnology, Bioengineering, Pharmaceutical sciences, or equivalent
Occupancy rate 100%
Vacancy type Research staff
Within the framework of an FWO/TBM-funded project, the candidate will perform research in the (pre-) clinical validation of the novel Nuclear Transfer (NT) technology in assisted reproductive technology for two specific indications, being (1) female-related infertility and (2) mitochondrial DNA (mtDNA) diseases. The NT technology involves the transfer of the nuclear genome from a patient’s diseased or inferior quality oocyte or zygote to a healthy donor counterpart from which the nuclear genome was removed. The resulting NT embryos contain the nuclear DNA from both prospective parents and the cytoplasm, including the mtDNA, originating from the donor. More recently, NT technology has also been proposed to overcome specific female-related infertility indications that could be attributed to inferior oocyte quality, for which generally oocyte donation is advised. The candidate will focus on the safety considerations in using NT technology, by extensive -omics analyses (genomic, transcriptomics, epigenomics) of NT embryos, next to the detection of mutations responsible for infertility or mitochondrial diseases.
The PhD position is available in the research groups of prof. dr. ir. Björn Menten (Center for Medical Genetics) and prof. dr. Björn Heindryckx (Ghent-Fertility And Stem cell Team).
Tasks:
Our labs offer the opportunity to work in a dynamic and multidisciplinary academic research environment with close interaction between clinicians and basic scientists and with (inter)national collaborations. Research stays abroad and attendance at international conferences are encouraged. The candidate will follow a PhD trajectory at Ghent University, which offers ample opportunities for education and training through the doctoral schools program.
WHAT WE CAN OFFER YOU
Send a motivation letter and curriculum vitae with detailed study results (per year) to Prof. Dr. Björn Menten (Email: Bjorn.Menten@UGent.be) or Prof. Dr. Björn Heindryckx (Email: Bjorn.Heindryckx@UGent.be).
Please also include extracurricular activities and the contact information of two references.
Ghent University is one of the top 100 universities in the Dutch language area, with more than 44,000 students and 15,000 staff members.
Besøk arbeidsgiverens side