Last application date Oct 29, 2024 00:00
Department TW06 - Department of Electronics and Information Systems
Contract Limited duration
Degree required diploma is Master of Science awarded by start data. In Physics, Mathematics, or closely related with high mathematical training (Engineering Physics, Biomedical Engineering,…).
Occupancy rate 100%
Vacancy type Research staff
We are seeking a motivated PhD student in biophysical modeling. The students will perform theoretical and computational research using simulations at the molecular scale. In the DYMEMO project we will search for computational methodologies to study the kinetics of drug transport through membranes. Since experiments often are too expensive or lack sufficient detail, molecular simulations can give insight in the dynamics of drug binding to proteins, or the permeation kinetics of those drug molecules through membranes. While such computational methodologies exist, new fundamental developments are needed to understand the ‘time’ aspects and to make the computations feasible with present-day computer power. The aim of the project is to extend the path sampling methodology to incorporate nonequilibrium kinetics, which is especially relevant for understanding cell death caused by a photoporation treatment. The PhD research will thus combine abstract thinking with highly relevant biomedical applications.
The student will be embedded in the Biophysical Models for Medical Applications (BioMMedA, https://biommeda.ugent.be) research group, which creates a motivating environment to perform research. BioMMedA is part of the Institute of Biomedical Technology (IBiTech), which is a hub of biophysicists and engineers working on biomedical research questions.
The PhD student will work towards a doctoral degree through the doctoral schools program of Ghent University under the supervision of Prof. An Ghysels. A contribution to teaching can also be part of the job content. This research is performed in close collaboration with international groups (e.g. the group of Prof. Titus van Erp at NTNU in Trondheim, Norway). Locally, collaborations within the Cancer Research Institute Ghent network (CRIG, Ghent, Belgium) are encouraged, especially for experimental validation of the research results, and international collaborations with other research groups are also possible.
We offer:
(1) You have excellent skills in physics/mathematics (for method development) and you enjoy abstract thinking.
(2) You are skilled in scientific programming, data analysis, and dealing with large data (computational tools for generating and analyzing data of complex molecular systems), for instance with Python (or equivalent).
(3) Ideally, you have also knowledge in statistical physics, biophysics or material physics, programming, scientific communication. Ideally, you have already some experience with molecular simulations. Knowledge of biology or chemistry is a strong point, but not necessary at the start of the PhD.
(4) You have a problem-solving, analytical mind, dedicated to overcoming technical challenges.
(5) You have an open attitude towards learning, and are driven, hard-working, committed to obtaining a PhD.
(6) You have good oral and written communication skills, with fluency in English.
Hiring will occur on a ongoing basis, so do not hesitate to apply before the deadline.
Ghent University is one of the top 100 universities in the Dutch language area, with more than 44,000 students and 15,000 staff members.
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