R&D in bioinformatics and computational modelling

About the LCSB

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg.
We conduct fundamental and translational research in the field of Systems Biology and Biomedicine - in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer's and Parkinson's disease and their contributing factors. The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary, and together we contribute to science and society.

The University of Luxembourg has the following vacancy at the Luxembourg Centre for Systems Biomedicine (LCSB) - Integrative Cell Signalling group: Research & Development Specialist.

Successful candidates will join the Integrative Cell Signalling group, led by Prof. Alexander Skupin, which performs interdisciplinary research in brain disorders. Specifically, the group focuses on mechanisms of brain disorders by multiscale approaches including multiomics characterization, bioinformatics analyses and mechanistic modelling. For more information, please visit our webpage.

The R&D specialist will support the analysis of mutation-induced impairments of ion channels with a focus on the sodium ion channel Nav1.1 by protein structure predictions and molecular dynamics simulations to perform advanced in silico drug screening as well as general bioinformatics analyses.

Your role

• General support of lab activities
• Performing molecular dynamics simulation
• Investigating in silico drug screening
• Molecular dynamics data integration
• Data interpretation and reporting of results
• Perform bioinformatics analyses for molecular data
• Participate in knowledge dissemination activities through the preparation of scientific publications or presentations in scientific venues
• Support funding applications (support hypothesis generation, conception, and grant writing)
• Participate in teaching activities (seminars and practicals)
• Support and tutoring of activity of students

For further information, please contact Prof. A. Skupin at

Your profile

• MSc in Life Sciences, Neurosciences, Computational or Systems Biology or related field
• Strong interest in interdisciplinary research
• Proven experience with high-performance computing
• Good command of data analysis
• Skills to autonomously conduct data analysis with solid understanding of statistics
• Experience with GROMACS or OpenMM are an asset
• Excellent written and oral communication skills in English with proven experience in the writing of scientific publications
• Excellent team-working, interpersonal skills, and ability to collaborate with local and international partners
• Enthusiasm and commitment to research
• Ability to think ahead as well as to troubleshoot

We offer

• Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the "University of the Greater Region" (UniGR)
• A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …

How to apply

Applications (in English) should contain the following documents:

• Detailed Curriculum Vitae including a list of publications
• Cover letter mentioning the reference number
• Copies of diploma and transcripts
• Name and addresses of three referees

Early application is highly encouraged, as the applications will be processed upon reception. Please apply ONLINE formally through the HR system. Applications by Email will not be considered.

All qualified individuals are encouraged to apply. In line with our values, the University of Luxembourg promotes an inclusive culture. We encourage applications from individuals of all backgrounds and are dedicated to upholding equality and respect for our employees and students.

General information:

• Contract Type: Fixed Term Contract 6 Month (with opportunity for extesnsion)
• Work Hours: Full Time 40.0 Hours per Week
• Location: Campus Belval
• Internal Title: Research and development specialist
• Job Reference: UOL06761

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