ANR-funded post-doctoral position NeuroCyto lab (Christophe Leterrier) at INP, Marseille

RESEARCHER PROFILE: Postdoc / R2: PhD holders 
RESEARCH FIELD(S)1: Biological sciences
MAIN SUB RESEARCH FIELD OR DISCIPLINES1: Biology

JOB /OFFER DESCRIPTION 
About the position
The NeuroCyto lab is looking to hire a postdoctoral fellow for an exciting project on novel mechanisms of microtubule turnover in neurons, in collaboration with collaboration with the lab of Manuel Théry and Laurent Blanchoin (CytoMorpho lab, ESPCI, Paris). The position is available from January 1st, 2024, and is funded for up to 3 years by ANR, with applications for fellowships being encouraged during the first year.

About the project
The Théry lab has discovered a new mechanism of microtubule turnover via in-lattice repair (Schaedel et al., 2015; Aumeier et al., 2016; Théry & Blanchoin, 2021) that we could recently visualize using super-resolution microscopy (Gazzola et al., 2022). We are now developing methods to visualize in-lattice repair within the dense arrays of neuronal microtubules, and are mapping microtubule turnover in neurons with unprecedented spatial and temporal resolution. The project will explore how in-lattice turnover impacts the establishment, maintenance and transformation of the unique cytoskeletal architecture in neurons, using a combination of single-cell manipulation and advanced microscopy approaches in neuronal cultures. You will drive this project with supervision and mentoring from established researchers in the NeuroCyto lab: devise experiments, acquire and analyze data, work with team members, and prepare publications

About the team and environment
The NeuroCyto lab is a thriving team of about 12 people, part of the Institute of Neurophysiopathology (INP) located on the Timone campus of Aix-Marseille University, in the center of Marseille. The overarching aim of the team is to understand how the neuronal cytoskeleton can build, maintain, and transform the neuronal organization and function. We have a recognized expertise in applying cutting-edge microscopy (live-cell, super-resolution) to neuronal cell biology, helped by a strong network of long-time collaborators. In the team, we aim to make ambitious and rigorous science by fostering a positive environment based on respect, team spirit, good communication and mentoring.
More info at: https://www.neurocytolab.org/postdoc/

TYPE OF CONTRACT: TEMPORARY / JOB STATUS: FULL TIME / HOURS PER WEEK:  39
APPLICATION DEADLINE:  31/12/2024 & TIME 12:00
ENVISAGED STARTING DATE: 01/01/2025
ENVISAGED DURATION: 36 months
JOB NOT FUNDED THROUGH AN EU RESEARCH FRAMEWORK PROGRAMME

WORK LOCATION(S): Institute of Neurophysiopathology (INP Lab) (CNRS-Aix-Marseille Université), 27 boulevard Jean Moulin, 13005 Marseille, France

WHAT WE OFFER: 
Salary according to the Aix-Marseille University scales, depending on experience.

Additional information: The Euraxess Center of Aix-Marseille Université informs foreign visiting professors, researchers, postdoc and PhD candidates about the administrative steps to be undertaken prior to arrival at AMU and the various practical formalities to be completed once in France: visas and entry requirements, insurance, help finding accommodation, support in opening a bank account, etc. More information on AMU EURAXESS Portal 

QUALIFICATIONS, REQUIRED RESEARCH FIELDS, REQUIRED EDUCATION LEVEL, PROFESSIONAL SKILLS, OTHER RESEARCH REQUIREMENTS

Skills/Qualifications
Required qualifications: Recent PhD degree in cell biology, neurobiology or a related biomedical field, with track record of publications and lab experience in one or more areas that include: cytoskeleton, neuronal cell biology, neuronal polarity, advanced microscopy (live-cell imaging, expansion microscopy). Highly motivated candidates with interest in areas of research at the intersection of neuronal cell biology, advanced microscopy and quantitative biology are strongly encouraged to apply.

Soft skills
Taste for interdisciplinary work, team spirit, ability to interact and collaborate with team members and collaborators, a general sense of camaraderie and motivation to learn.

Specific Requirements
Required: Experience with cell culture, sample preparation, microscopy.
Desirable: Experience in cytoskeleton study, neuronal cell culture, live-cell imaging, expansion microscopy.
Would be a plus: Coding skills for quantification workflows.
Languages: English
Level: Good

REQUESTED DOCUMENTS OF APPLICATION, ELIGIBILITY CRITERIA, SELECTION PROCESS
Please send a CV, name of 2 or more references, and a motivation letter stating why we should work together on this project to christophe.leterrier@univ-amu.fr. Interviews will be conducted during the application period so don’t hesitate to apply early.

HOW TO APPLY: christophe.leterrier@univ-amu.fr